Jack D. Leber: search on Z-Library

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1

Slow binding inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

Louis-Flamberg, Pearl, Peishoff, Catherine E., Bryan, Deborah L., Leber, Jack, Elliott, John D., Metcalf, Brian W., Mayer, Ruth J.

Journal:

Year:

1990

Language:

english

File:

PDF, 767 KB

english, 1990

2

Generation of in vitro B-CLL specific HLA class I restricted CTL responses using autologous dendritic cells pulsed with necrotictumor lysate

Suresh, Kalathil, Fraser, Graeme, Scheid, Elizabeth, Leber, Brian, Gauldie, Jack, Foley, Ronan

Journal:

Leukemia and Lymphoma

Year:

2006

Language:

english

File:

PDF, 745 KB

english, 2006

3

p-Chlorophenyl Methyl Sulfide, p-Chlorophenyl Methyl Sulfoxide, and p-Chlorophenyl Methyl Sulfone. I. Acute Toxicity and Bacterial Mutagenicity Studies

Leber, A. Philip, Dacre, Jack C., Thake, Daryl C., Mays, Dennis C.

Journal:

Journal of the American College of Toxicology

Year:

1993

Language:

english

File:

PDF, 476 KB

english, 1993

4

1,3-Diarylindan-2-carboxylic Acids, Potent and Selective Non-Peptide Endothelin Receptor Antagonists

Elliott, John D., Lago, M. Amparo, Cousins, Russell D., Gao, Aiming, Leber, Jack D., Erhard, Karl F., Nambi, Ponnal, Elshourbagy, Nabil A., Kumar, Chandrika

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 572 KB

english, 1994

5

The preparation of 9-alkylthiofluorenes from biphenyl-2-carboxaldehydes

Jack D. Leber, John D. Elliott

Journal:

Tetrahedron Letters

Year:

1989

Language:

english

File:

PDF, 121 KB

english, 1989

6

Identification of 4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a Novel Inhibitor of AKT Kinase

Rhodes, Nelson, Leber, Jack D., Clark, Tammy J., Keenan, Richard M., Lafrance, Louis V., Li, Mei, Safonov, Igor G., Takata, Dennis T., Venslavsky, Joseph W., Heerding, Dirk A.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 886 KB

english, 2008

7

A revised structure of sibiromycin

Leber, Jack D., Hoover, John R. E., Holden, Kenneth G., Johnson, Randall K., Hecht, Sidney M.

Journal:

Journal of the American Chemical Society

Year:

1988

Language:

english

File:

PDF, 244 KB

english, 1988

8

Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A synthase by antibiotic 1233A and other β-lactones

Ruth J. Mayer, Pearl Louis-Flamberg, John D. Elliott, Mark Fisher, Jack Leber

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 433 KB

english, 1990

9

Synthesis of structural analogs of leukotriene B4 and their receptor binding activity

Kingsbury, William D., Pendrak, Israil, Leber, Jack D., Boehm, Jeffery C., Mallet, Brenda, Sarau, Henry M., Foley, James J., Schmidt, Dulcie B., Daines, Robert A.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 1.77 MB

english, 1993

10

p-Chlorophenyl Methyl Sulfide, p-Chlorophenyl Methyl Sulfoxide, and p-Chlorophenyl Methyl Sulfone. II. Subchronic Effects in Rodents and Rhesus Monkeys

Thake, Daryl C., Mays, Dennis C., Leber, A. Philip, Dacre, Jack C.

Journal:

Journal of the American College of Toxicology

Year:

1993

Language:

english

File:

PDF, 934 KB

english, 1993

11

Tetrasubstituted pyridines as potent and selective AKT inhibitors: Reduced CYP450 and hERG inhibition of aminopyridines

Hong Lin, Dennis S. Yamashita, Ren Xie, Jin Zeng, Wenyong Wang, Jack Leber, Igor G. Safonov, Sharad Verma, Mei Li, Louis LaFrance, Joseph Venslavsky, Dennis Takata, Juan I. Luengo, Jason A. Kahana, Sh

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 781 KB

english, 2010

12

p-Chlorophenyl Methyl Sulfide, p-Chlorophenyl Methyl Sulfoxide, and p-Chlorophenyl Methyl Sulfone. III. Toxicokinetics and Metabolism in Rats and Rhesus Monkeys

Dacre, Jack C., Leber, A. Philip, Mays, Dennis C.

Journal:

Journal of the American College of Toxicology

Year:

1993

Language:

english

File:

PDF, 577 KB

english, 1993

13

Correction: Slow binding inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Erratum to document cited in CA112(23):212921g]

Louis-Flamberg, Pearl, Peishoff, Catherine E., Bryan, Deborah L., Leber, Jack, Elliott, John D., Metcalf, Brian W., Mayer, Ruth J.

Journal:

Year:

1990

Language:

english

File:

PDF, 108 KB

english, 1990

14

Aminofurazans as potent inhibitors of AKT kinase

Meagan B. Rouse, Mark A. Seefeld, Jack D. Leber, Kenneth C. McNulty, Lihui Sun, William H. Miller, ShuYun Zhang, Elisabeth A. Minthorn, Nestor O. Concha, Anthony E. Choudhry, Michael D. Schaber, Dirk

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.30 MB

english, 2009

15

Discovery of Aminofurazan-azabenzimidazoles as Inhibitors of Rho-Kinase with High Kinase Selectivity and Antihypertensive Activity

Leber, Jack D., Marino,, Joseph P., Stavenger, Robert A., Cui, Haifeng, Dowdell, Sarah E., Franz, Robert G., Gaitanopoulos, Dimitri E., Goodman, Krista B., Hilfiker, Mark A., Ivy, Robert L.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 103 KB

english, 2007

16

Lysine 182 of Endothelin B Receptor Modulates Agonist Selectivity and Antagonist Affinity: Evidence for the Overlap of Peptide and Non-peptide Ligand Binding Sites

Lee, Jonathan A., Brinkmann, Joyce A., Longton, Enrique D., Peishoff, Catherine E., Lago, M. Amparo, Leber, Jack D., Cousins, Russell D., Gao, Aiming, Stadel, Jeffrey M.

Journal:

Year:

1994

Language:

english

File:

PDF, 748 KB

english, 1994

17

Photochemistry of 17.beta.-hydroxyestra-5(10), 9(11)-dien-3-one. Synthesis of AB spiro steroids

Williams, John R., Salama, Hani, Leber, Jack D.

Journal:

Journal of Organic Chemistry

Year:

1977

Language:

english

File:

PDF, 452 KB

english, 1977

18

Novel Conversion of 17-Oxo Steroids into the Corresponding α,β-Unsaturated D-Homo-lactone by Selenylation-Dehydroselenylation

WILLIAMS, John R., LEBER, Jack D.

Journal:

Year:

1977

File:

PDF, 122 KB

1977

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